Key: Win : Draw : Loss
| Date | Home | Away | Ref | ||
|---|---|---|---|---|---|
| 06/08/2011 | Port Vale | 2 | 2 | Crawley Town | D Webb |
| 13/08/2011 | Barnet | 1 | 3 | Port Vale | F Graham |
| 16/08/2011 | Burton | 1 | 1 | Port Vale | G Salisbury |
| 20/08/2011 | Port Vale | 4 | 1 | Accrington | C Berry |
| 27/08/2011 | Port Vale | 2 | 3 | Southend | J Moss |
| 03/09/2011 | AFC Wimbledon | 3 | 2 | Port Vale | G Scott |
| 10/09/2011 | Plymouth | 0 | 2 | Port Vale | C Pawson |
| 13/09/2011 | Port Vale | 3 | 2 | Bradford | D Whitestone |
| 17/09/2011 | Port Vale | 2 | 3 | Shrewsbury | P Gibbs |
| 24/09/2011 | Crewe | 1 | 1 | Port Vale | N Swarbrick |
| 01/10/2011 | Port Vale | 2 | 0 | Rotherham | P Tierney |
| 08/10/2011 | Gillingham | 1 | 1 | Port Vale | S Hooper |
| 14/10/2011 | Port Vale | 3 | 0 | Northampton | A Madley |
| 22/10/2011 | Port Vale | 0 | 4 | Morecambe | D Mohareb |
| 25/10/2011 | Bristol Rvs | 0 | 3 | Port Vale | G Sutton |
| 29/10/2011 | Oxford | 2 | 1 | Port Vale | M Haywood |
| 05/11/2011 | Port Vale | 0 | 2 | Swindon | D Sheldrake |
| 19/11/2011 | Cheltenham | 2 | 0 | Port Vale | R Madley |
| 25/11/2011 | Port Vale | 0 | 0 | Torquay | K Stroud |
| 10/12/2011 | Dag and Red | 1 | 2 | Port Vale | S Mathieson |
| 17/12/2011 | Port Vale | 4 | 0 | Aldershot | N Miller |
| 26/12/2011 | Hereford | 1 | 2 | Port Vale | A Woolmer |
| 31/12/2011 | Macclesfield | 2 | 1 | Port Vale | P Tierney |
| 02/01/2012 | Port Vale | 1 | 2 | Cheltenham | A Haines |
| 07/01/2012 | Southend | 3 | 0 | Port Vale | B Malone |
| 14/01/2012 | Port Vale | 1 | 2 | AFC Wimbledon | A Davies |
| 21/01/2012 | Rotherham | 0 | 1 | Port Vale | D Mohareb |
| 28/01/2012 | Port Vale | 1 | 0 | Plymouth | I Williamson |
| 14/02/2012 | Bradford | 1 | 1 | Port Vale | T Harrington |
| 18/02/2012 | Port Vale | 2 | 1 | Gillingham | D Drysdale |
| 25/02/2012 | Northampton | 1 | 2 | Port Vale | G Ward |
| 28/02/2012 | Port Vale | 1 | 1 | Crewe | G Scott |
| 03/03/2012 | Accrington | 2 | 2 | Port Vale | R Lewis |
| 06/03/2012 | Port Vale | 3 | 0 | Burton | S Mathieson |
| 10/03/2012 | Port Vale | 1 | 2 | Barnet | G Eltringham |
| 17/03/2012 | Crawley Town | 3 | 2 | Port Vale | M Brown |
| 20/03/2012 | Port Vale | 1 | 0 | Hereford | A D'Urso |
| 24/03/2012 | Torquay | 2 | 1 | Port Vale | D Sheldrake |
| 31/03/2012 | Port Vale | 0 | 1 | Dag and Red | L Collins |
| 06/04/2012 | Aldershot | 1 | 2 | Port Vale | G Salisbury |
| 09/04/2012 | Port Vale | 1 | 0 | Macclesfield | C Pawson |
| 14/04/2012 | Morecambe | 0 | 0 | Port Vale | D Deadman |
| 17/04/2012 | Shrewsbury | 1 | 0 | Port Vale | A Madley |
| 21/04/2012 | Port Vale | 1 | 0 | Bristol Rvs | D Mohareb |
| 28/04/2012 | Swindon | 5 | 0 | Port Vale | D Phillips |
| 05/05/2012 | Port Vale | 3 | 0 | Oxford | D Drysdale |